---
product_id: 748223486
title: "API Stress Zyme, 64-Ounce by Aquarium Pharmaceuticals"
brand: "api"
price: "R$3081"
currency: BRL
in_stock: true
url: https://www.desertcart.com.br/products/748223486-api-stress-zyme-64-ounce-by-aquarium-pharmaceuticals
store_origin: BR
region: Brazil
---

# treats up to 3840 gallons 64 oz powerful bio-filter booster breaks down toxic ammonia & nitrites API Stress Zyme, 64-Ounce by Aquarium Pharmaceuticals

**Brand:** api
**Price:** R$3081
**Availability:** ✅ In Stock

## Summary

> ♻️ Keep your tank thriving—because your fish deserve the best!

## Quick Answers

- **What is this?** API Stress Zyme, 64-Ounce by Aquarium Pharmaceuticals by api
- **How much does it cost?** R$3081 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.com.br](https://www.desertcart.com.br/products/748223486-api-stress-zyme-64-ounce-by-aquarium-pharmaceuticals)

## Best For

- api enthusiasts

## Why This Product

- Trusted api brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Massive Coverage:** One bottle treats up to 3840 gallons—perfect for large tanks or multiple setups
- • **Toxin Terminator:** Effectively breaks down harmful ammonia and nitrites to protect your fish
- • **Fish-Friendly Formula:** Promotes healthier fish and optimal oxygen levels for vibrant aquatic life
- • **Effortless Maintenance:** Continuous use keeps your aquarium cleaner without refrigeration
- • **Maximize Aquarium Health:** Boosts biological filter development for crystal-clear water

## Overview

API Stress Zyme is a 64-ounce liquid treatment designed to enhance biological filter growth and break down harmful organic compounds like ammonia and nitrites. Suitable for treating up to 3840 gallons, it ensures cleaner water, healthier fish, and sustained oxygen levels without the need for refrigeration.

## Description

Improves the development of the biological filter and helps clean a dirty aquarium; Breaks down organic compounds that cause dangerous conditions such as as ammonia and nitrite poisoning and low oxygen levels; Continuous use assures an active biological filter, cleaner aquarium, healthier fish and good water quality; No refrigeration necessary; Treats 3840 gallons

## Features

- API Stress Zyme, 64-Ounce
- 64 oz

## Technical Specifications

| Specification | Value |
|---------------|-------|
| Item model number | 56J |
| Is Discontinued By Manufacturer | No |
| Item Form | Liquid |
| Volume | 828 |
| batteries required | No |
| Batteries Included | No |

## Product Details

- **Brand:** API
- **Liquid Volume:** 64 Fluid Ounces
- **Item Weight:** 1.86 kg
- **Item Form:** Liquid
- **Manufacturer:** Aquarium Pharmaceuticals

## Images

![API Stress Zyme, 64-Ounce by Aquarium Pharmaceuticals - Image 1](https://m.media-amazon.com/images/I/81VdRQaYCRL.jpg)
![API Stress Zyme, 64-Ounce by Aquarium Pharmaceuticals - Image 2](https://m.media-amazon.com/images/I/81DP-svsA7L.jpg)
![API Stress Zyme, 64-Ounce by Aquarium Pharmaceuticals - Image 3](https://m.media-amazon.com/images/I/91Wlg1zGY2L.jpg)
![API Stress Zyme, 64-Ounce by Aquarium Pharmaceuticals - Image 4](https://m.media-amazon.com/images/I/91M80WNPvvL.jpg)
![API Stress Zyme, 64-Ounce by Aquarium Pharmaceuticals - Image 5](https://m.media-amazon.com/images/I/91rbAhq0W4L.jpg)

## Questions & Answers

**Q: Can I mix this with API Quick Start and API Stress Coat+ in a gallon every time I do water changes weekly? Or just pour it directly in my 5.5 tank?**
A: In short, you don't need the Stress Zyme if you already are using the Quick Start.  Here's a longer answer:The API Stress Coat is primarily a de-chlorinator and has aloe added to help maintain a healthy slime coat on the fish so this should always be added to the water and mixed before adding to the tank.  The API Quick Start is meant to jump start the biological cycling of a tank and is only needed for new tanks or potentially semi established tanks that have a spike in ammonia and nitrite levels which could be caused by adding more fish.  You can stop using this once your water chemistry has stabilized.  API Stress Zyme is very similar in function to the Quick Start and is generally chosen to improve water clarity or stabilize chemistry in more established tanks.    You don't need to use both simultaneously and would probably never see the difference compared to using just one.  On another note, I always add my bacteria after there is no chance there is any chlorine so they have a better chance of proliferating.  I would add either the Quick Start or the Stress Zyme the day after a water change, directly into the tank.

**Q: can i mix stress coat, stress zyme and tap water conditioner? if so what amount of each should i mix? doing this harm my fishes?**
A: Stress Coat and water conditioner is the same. ( stress Coat is water conditioner ). if you use both at the same time that you double it up. Maybe it is nothing will happening . But, it is not necessary to do that.

**Q: How long this product can be stored before it expires?  Also, would its effectiveness reduce during long time storage?**
A: As for length of time you can store, I use it weekly and it lasts for about four months or so. Does not seem to lose effectiveness in that time.

**Q: What is the expiration date on this Stress Zyme?  It seems very inexpensive.**
A: There is an expiration date on the bottle, however, these are live bacteria and once the bottle is open the shelf life is cut in half. Same as Seachems Pristine. Buy the size bottle for your tank. There is 250ml and 500 or 750ml, depending on the brand. My personal and professional advice is buy the smaller one 1st and see how much you go through, follow the instructions completely. They work well, keeps the glass cleaner longer. Also very important, make sure the aeriation is adequate and they say to change the filters 1st. If you have the $$ go for it. Best and least expensive and just as sufficient, is to change them half way before you normally change out your filters. API Stress zyme seems to keep its life span quite a while after opening. But trust me, you'll use it up way before it expires. Compared to the other similar products, this one seems to leave more of a brownish pile on the corners or underneath Ornaments, whis in turn will have to be vacuumed, netted or a baster for cooking depending on the size of your tank. 👍

## Frequently Bought Together

- API STRESS ZYME Freshwater and Saltwater Aquarium Cleaning Solution 64-Ounce Bottle
- API STRESS COAT Aquarium Water Conditioner 64-Ounce Bottle
- API QUICK START Freshwater and Saltwater Aquarium Nitrifying Bacteria 32-Ounce Bottle

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*Product available on Desertcart Brazil*
*Store origin: BR*
*Last updated: 2026-02-01*